We are pleased to announce that our recent study, Efficacy of Spore-Forming Bacilli Supplementation in Patients with Mild to Moderate Elevation of Triglycerides: A 12-Week Randomized, Double-Blind, Placebo-Controlled Trial, has just been published in Integrative Medicine: A Clinician’s Journal.
Approximately 1/3 of the population has elevated triglyceride levels (> 150 mg/dL) in the bloodstream, or hypertriglyceridemia (HT). In addition to cholesterol levels like LDL and HDL, elevated levels of triglycerides are also commonly used as indicators for heart disease risk.
Due to the metabolic functions of the gut microbiome, an imbalance of gut bacteria (gut dysbiosis) can increase serum triglycerides by increasing intestinal permeability and allowing for bacterial endotoxin translocation into circulation.
Finally, excessive intake of certain dietary fat stimulates triglyceride production in the liver. As triglycerides circulate the body, they can contribute to plaque formation in arteries, fatty build-up around the liver, and systemic inflammation.
Campbell AW, Sinatra D, Zhang Z, et al. Efficacy of Spore Forming Bacilli Supplementation in Patients with Mild to Moderate Elevation of Triglycerides: A 12 week, Randomized, Double-Blind, Placebo Controlled Trial. Integrative Medicine. 2020;19(2):18-23.