A 100% spore-based, broad-spectrum probiotic shown to maintain healthy gut barrier function. This unique all-spore formula effectively RECONDITIONS the gut by promoting microbial diversity and maintaining key health-promoting, commensal gut bacteria.

MegaSporeBiotic™ does not require refrigeration and maintains a healthy gut microbiome.

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At a glance

MegaSporeBiotic is a probiotic blend of 5 Bacillus spores that have been shown to maintain healthy gut barrier and immune function. The bi-phasic life cycle of the Bacillus spores allows them to remain dormant in harsh environments until they reach more favorable environments like the human gastrointestinal tract.

Once inside the large intestine, these dormant spores can change into their active, vegetative forms and begin colonizing in the gut. This unique probiotic blend aims to RECONDITION the gut instead of reseeding with probiotic strains that cannot survive digestion or colonize the gut. MegaSporeBiotic has quickly become a household favorite among health practitioners and consumers alike.

Ingredients and formula

With the launch of MegaSporeBiotic™, Microbiome Labs completely disrupted the probiotic industry, shifting the focus from reseeding to reconditioning the gut microbiome with the help of Bacillus spores.

Dosing instructions

Start with 1/2 capsule or 1 full capsule with food and slowly increase to 2 capsules per day using the following protocol.

Week 1

1 capsule every other day

Week 2

1 capsule daily

Week 3+

2 capsules daily

If 1 capsule every other day causes side effects, try starting with 1/2 capsules or even 1/4 capsule in some cases. Possible side effects may include abdominal cramping, loose stools, and changes in bowel movements. Though these side effects may be uncomfortable, they are a sign that the product is working! Side effects should resolve within 2-3 days.


Robert T

Our office LOVES this product. We can’t keep it on the shelf. We use the product ourselves and our patients are excited to try it. It has GREAT science behind it. We are always learning something new when we listen to Kiran talk about the products. We look forward to sharing this product with more of our patients.

April 27, 2018

Robert T


Angie B

I had been on Digestive Advantage for 5 years and saw little improvement. Within 3 days of being on MegaSpore I could not believe how much better I felt and still continue to feel since switching. The Best Probiotic out there!!!!

April 27, 2018

Angie B


Kathy W

The most effective probiotic I have ever used, both personally and professionally.

July 23, 2017

Kathy W


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