Zenbiome DUAL

Zenbiome™ DUAL is a dual-action probiotic combination designed to support both digestive comfort and mood self-regulation.**

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At a glance

Key Features

Dosage

Cognitive Support Studies

Zenbiome™ DUAL is a dual-action probiotic combination designed to support both digestive comfort and mood self-regulation. This unique, holistic solution targets the gut-brain axis and is clinically demonstrated to support the relief of occasional gastrointestinal (GI) discomfort and its associated psychological stress. Powered by two innovative probiotic strains, Zenbiome™ DUAL provides around-the-clock digestive maintenance, supporting optimal gut health and overall well-being.**

Zenbiome™ DUAL was designed to:

Support digestive comfort**
May relieve occasional episodes of abdominal discomfort, gas, bloating, diarrhea, and/or constipation**
Supports the gut-brain axis**
Maintains normal, regular digestive processes*
Supports mood self-regulation**
Helps address and overcome occasional stress**
Maintains cortisol levels already within a normal range**
Maintains energy, vitality, and mental acuity**
Supports balanced sleep**
Provides health-supportive bacteria for the GI tract**

Dosing Instructions

Take 2 capsules daily with a meal or as directed by your healthcare practitioner.

Cognitive Support Studies:

Form/Duration	Study Details and Results	Reference
*Bifidobacterium longum* 1714® (Zenbiome Cope™ & Sleep™) 4 weeks	Placebo-controlled study 22 participants 1714® strain supported cortisol levels and reduced perceived stress levels throughout the study compared to the placebo group. Significantly lower perceived stress levels in those participants taking B. longum 1714® compared to the placebo group. Bifidobacterium longum 1714® (Zenbiome Cope™ & Sleep™)	DOI: 10.1038/tp.2016.191
*Bifidobacterium longum* 1714® (Zenbiome Cope™ & Sleep™) 4 weeks	Randomized, double-blinded, placebo-controlled trial 40 participants 1714® strain supported relaxation reduced stress, and enhanced mood Difference of neural activity change during resting state in theta band after 1714®- promoted theta brainwave activity at rest, compared to the placebo group. Difference of neural activity change during resting state in beta 2 band after 1714® supported body’s adaptation to beta 2 brain wave activity at rest, compared to the placebo group.	DOI: 10.14309/ajg.0000000000000203

Cognitive Support Studies Continued:

Form/ Duration	Study Details and Results	References
*Bifidobacterium longum* 1714® (Zenbiome Cope™ & Sleep™) 4 weeks	Double-blind, randomized, placebo-controlled, repeated measures, cross-over design 20 participants Overall sleep quality and duration of sleep improved significantly in the probiotic treated group during exam stress compared with the placebo treated group.	DOI: 10.1016/j.bbih.2020.100174
Bifidobacterium longum 1714® and Bifidobacterium longum 35624® (Zenbiome Cope™ & Sleep™) 8 weeks	Open label exploratory study 40 participants This exploratory open-label study found that 82% of subjects had significantly improved issues after 8 weeks, with 66% of subjects significantly improving after 4-weeks (issue severity score change of ≥ 50) in the moderate to severe group. The combination solution improved each of the individual issues (occasional abdominal discomfort, distension, bowel satisfaction), as well as an improvement in their quality of life. Participants in this group also had a significant improvement in their morning cortisol awakening response, a physiological biomarker of stress, after 4-weeks.	DOI: 10.1111/nmo.14477